How to apply your denture Clean and dry your denture. Apply in three short short strips not too close to the edges and edge of the denture. Rinse your mouth before putting on the denture. Adjust the dental prosthesis in the mouth, press firmly and bite for a few seconds to ensure attachment. How to remove the denture Rinse your mouth with water. Remove the denture slowly with rocking movements. Eliminate the remains of fixative cream from the mouth and prosthesis with warm water and a soft brush. Use pads or cleaning foam to clean the denture.